BelekUniversity Institutional Repository
DSpace@Belek digitally stores academic resources such as books, articles, dissertations, bulletins, reports, research data published directly or indirectly by Antalya Belek University at international standards, helps track the academic performance of the university, provides long term preservation for resources and makes publications available to Open Access in accordance with their copyright to increase the effect of publications.
Recent Submissions
Clinical and sociodemographic differences in adult women and men with obsessive-compulsive disorder
(Yerküre Tanıtım & Yayıncılık Hizmetleri A.Ş., 2024) Çoban, Deniz Adnan; Tan, Oğuz; Gündoğmuş, İbrahim
Objective: Gender is related to differences in the prevalences, manifestations and comorbidities of mental disorders. Findings on the effect of sex on adults with obsessive-compulsive disorder (OCD) are limited and inconsistent. We aimed to compare male and females with OCD in a large sample of adults. Methods: We included 559 patients with OCD (299 females, 50.68%). We employed the Yale-Brown Obsession and Compulsion Scale (Y-BOCS), Hamilton Depression Rating Scale-17 (HDRS-17) and Beck Anxiety Inventory (BAI). We gathered data about the onset of illness, the years of education, marital status, long-term unemployment, history of hospitalization and suicide attempts, lifetime attention deficit and hyperactivity disorder (ADHD), tic disorder, alcohol use disorder (AUD), substance use disorder (SUD), smoking and symptom dimensions. Results: The Y-BOCS, HDRS-17 and BAI scores were significantly higher in women. Men were characterized by earlier onset of OCD, younger age, longer years of education, higher prevalence of past or current tic disorders and higher frequency of AUD/SUD and smoking. Ratio of being married was higher among women whereas most of males were never-married. History of suicide attempt was more common among women. Conclusion: Our research offers additional support for variations in clinical characteristics of OCD based on gender. It is essential to investigate the biological foundation of gender differences on OCD.
Automated diagnosis of Alzheimer's Disease using OCT and OCTA: a systematic review
(IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 2024) Turkan, Yasemin; Boray Tek, F.; Arpaci, Fatih; Arslan, Ozan; Toslak, Devrim; Bulut, Mehmet; Yaman, Aylin
Retinal optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) have emerged as promising, non-invasive, and cost-effective modalities for the early diagnosis of Alzheimer's disease (AD). However, a comprehensive review of automated deep learning techniques for diagnosing AD or mild cognitive impairment (MCI) using OCT/OCTA data is lacking. We addressed this gap by conducting a systematic review using the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. We systematically searched databases, including Scopus, PubMed, and Web of Science, and identified 16 important studies from an initial set of 4006 references. We then analyzed these studies through a structured framework, focusing on the key aspects of deep learning workflows for AD/MCI diagnosis using OCT-OCTA. This included dataset curation, model training, and validation methodologies. Our findings indicate a shift towards employing end-to-end deep learning models to directly analyze OCT/OCTA images in diagnosing AD/MCI, moving away from traditional machine learning approaches. However, we identified inconsistencies in the data collection methods across studies, leading to varied outcomes. We emphasize the need for longitudinal studies on early AD and MCI diagnosis, along with further research on interpretability tools to enhance model accuracy and reliability for clinical translation.
Effect of process parameters on stevioside and rebaudioside a content of stevia extract obtained by decanter centrifuge
(WILEY, 2021) Arslan Kulcan, Aslı; Karhan, Mustafa
The aim of this research is to determine the possibility of decanter extraction for the isolation of steviol glycosides from stevia leaves. Extraction parameters such as temperature, time, and leaf/water ratio were optimized by using Response Surface Methodology. The optimal combination determined as a result of optimization studies was 25 degrees C, 1/27.6 leaf/water ratio, and 105 min extraction time. Under these conditions, experiments were carried out at three different speeds of 4,500, 4,900, and 5,280 rpm (2,264, 2,684, 3,117 g, respectively) in a decanter extraction system to investigate the effect of rotational speed. The amount of stevioside in samples obtained at 4,500, 4,900, and 5,280 rpm was 1080.82, 1919.18, and 2507.35 mg/L, respectively. The amount of rebaudioside A was 761.34, 1417.17, and 1801.93 mg/L, respectively. Results showed that the rotational speed of the decanter had a considerable effect on all the parameters examined. Practical applications Stevia is a product that is widely used in food formulations in the scope of combating obesity and diabetes. In this study, the decanter was applied for the first time to extract stevia leaves and optimum process conditions for decanter extraction of steviol glycosides were determined. It has been observed that stevia extraction can be successfully performed at 25 degrees C with high efficiency using decanter. The yield of the extract increased with increasing decanter rotational speed. The decanter extracted 73% of the total stevioside and rebaudioside A present in the leaves. The results of this study may be used by manufacturers who want to process the stevia plant with more economical and environmentalist approaches.
Relations arising from a family of combinatorial numbers and bernstein type basis functions
(AMER INST PHYSICS, 2018) Küçükoğlu, İrem; Şimşek, Yılmaz
The aim of this paper is to give some combinatorial sums, identities and relations related to a family of combinatorial numbers and the Bernstein type basis functions. With the help of generating functions for the combinatorial numbers from this aforementioned family, we give some functional equations. By using these functional equations, we obtain several relationships including these combinatorial numbers and the Bernstein type basis functions. Moreover, we provide not only some identities, but also applications including combinatorial sums, integrals, the combinatorial numbers, the extended Bersntein basis functions, and the beta function.
Thermal inactivation of airborne SARS-CoV-2 by an electric fan heater in winter and defining conditions to ensure that all the air passes through the fan
(ASME, 2024) Canpolat, Murat; Şakalar, Çağrı; Bozkurt, Serhat; Çoban, Ahmet Yılmaz; Karacaylı, Deniz; Toker, Emre
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spread, especially in closed environments, by airborne transmission. The study aims to assess the thermal inactivation of airborne SARS-CoV-2 in a 30 m(3) test room as a function of outlet temperature, airflow rate, and operating time of an electric heater, then define a condition to ensure that all air in the room passes through the electric heater. Aerosolized SARS-CoV-2 was delivered to the test room at an ambient temperature of 20 degrees C and 40% humidity. Two electric heaters with different powers and airflow rates were operated respectively in the test room to compare their efficiencies in the inactivation of airborne SARS-CoV-2. The first and second electric heaters had power, airflow rates, and outlet temperatures of 1.5 kW, 44 m(3)/h, 220 degrees C, and 3 kW, 324 m(3)/h, and 150 degrees C, respectively. A fan drew the outside air into the heater. In the first experiment, a 1.5 kW electric heater was operated in the test room for 80 min. In the second experiment, a 3 kW electric heater was used in the test room for 75 min. Airborne SARS-CoV-2 in the test room was inactivated by 99.00% and 99.96% in the first and second experiments, respectively. A condition is defined to ensure that all the air in the room passes at least once through the electric heater fan.
